UNIOSUN Staff Profile
Discover the People Behind Our Academic Excellence.
ASIYANBOLA Isaac Damilare
Assist. Lecturer
COLLEGE OF HEALTH SCI.
PHARMACOLOGY & THERAPEUTICS
Brief Educational Profile
Doctor of Philosophy (Pharmacology) (In View)
Master of Science (Pharmacology, 60 B+) 2023
Bachelor of Science (Biochemistry) (2nd class lower division) 2014
Academic Profiles
ORCID
Google Scholar
https://scholar.google.com/citations?user=GdYN5TsAAAAJ&hl=en
ResearchGate
Curriculum Vitae
Current/Recent Research
My research interest involves the investigation of pharmacological potentials of selected medicinal plants in the mitigation of neurological syndromes (N.S) in cerebral malaria (CM) via the use of experimental CM model. The germane factor determining plant of choice is the literature ascertained pharmacological activities – including but not limited to: antioxidant, anti-inflammatory, antimalarial, anticonvulsant and other activity that might be involved in CM mitigation such as nitric oxide and cytokines-inducing pharmacological properties. For my Master’s degree, I investigated the pharmacological potentials of graded doses of the essential oils of Curcuma aeruginosa and in combination with quinine (standard) in the progression of CM. This was monitored via selected screening panel which include – parasitemia assessment, survival rate, SHIRPA functional behavioural assessment and histology of the brain tissue. This research work has been published in Phytomedicine plus, Elsevier. I am extending the concluding part of my M.Sc. research for my PhD. I shall be incorporating computational biology, network pharmacology, and bio-assaying of drug agent and implicated cytokines/ chemokines in brain and blood of CM induced mice. This is in the view to determine phytochemical component(s) in the oil that could serve as drug-lead in the management of N.S of CM.
Selected Recent Publications
- 1.Animashaun O. T.; Ogunleye F. N.; Ayankunle A. A.; Wakeel O. K.; Animashaun S. O.; Aremu O. S.; Isaac D. Asiyanbola; Akinsola E. B.; Adeniran Y. D.: Renoprotective Effects of the Ethanol Leaf Extract of Nymphaea lotus (Linn.) in Glycerol-Induced Acute Kidney Injury in Rats: Journal of Pharmacological Sciences and Experimental Therapeutics (Official Journal of the Nigerian Society for Pharmacological Sciences and Experimental Therapeutics), ISSN 3115 – 6487, 2025.
- 2.Ayankunle A. A.; Kolawole O. T.; Ayankunle F. O.; Wakeel O. K.; Animashaun O. T.; Mohammed H. O.; Ogunleye F. N.; Isaac D. Asiyanbola; Aremu O. S.; Atere T. G.; Ojurongbe O.: Pregabalin: Demonstration of Higher Antimalarial Activities Than Artesunate in an Animal Model and Proposed Mechanism of Action: Pan African Journal of life sciences, Volume 9, No. 2, August 2025 Pages 547-554 DOI: 10.36108/pajols/5202/90.0271
- 3.Daniyan M. O.; Adeoye O. B.; Osirim E.; Isaac D. Asiyanbola: The effect of Bitter Honey against cerebral malaria-induced inflammasome cell death: Network pharmacology-based in-silico evaluation: Biomeditsinskaya Khimiya, 2024 vol. 70(6), pp. 442-455; DOI: 10.18097/PBMC20247006442
- 4.Faloye K. O.; Ambali O. A.; Ogundele S. B.; Tripathi M. K.; Adesida S. A.; Isaac D. Asiyanbola; Fakola E. G.; Obaidullah A. J.; Alotaibi J. M.; Oguntimeyin S. A.: Elucidating the antimalarial activity of Pityriacitrin isolated from Strophanthus hispidus (DC) whole plant extract: A detailed experimental and in-silico investigation; Journal of Molecular Structure 2024: 1318(2); https://doi.org/10.1016/j.molstruc.2024.139268
- 5.Isaac D. Asiyanbola; Daniyan M. O.; Opoggen T. S.; Olayemi I. O.; Adeoye O. B.; Ekundina V. O.; Oyemitan I. A.: Neuroprotective potentials of the essential oil of Curcuma aeruginosa Roxburg rhizomes in mice with cerebral malaria: Phytomedicine plus (2024), doi: https://doi.0rg/10.1016/j.phyplu.2024.100581
- 6.Daniyan M. O.; Ogunyemi T. H.; Olawuni I. J.; Isaac D. Asiyanbola; Adelodun S. T.; Opoggen T. S.; Oyemitan I. A.: Toxicity profiling of the co-administration of the essential oil of Piper guineense and quinine in rats: Universal Journal of Pharmaceutical Research 2023; 8(6): 32-42. Doi: https://doi.org/10.22270/ujpr.v8i61037
- 7.Ogundele S. B.; Oriola A. O.; Oyedeji A. O.; Isaac D. Asiyanbola; Agbeti E. A.; Olubiyi
- O. O.; Olorunmola F. O.; Babalola K.; Yusuf B. A.; Agbedahunsi J. M.: Antiplasmodial activity of chemical constituents of Artocarpusaltilis (Parkinson ex F. A. Zorn) Fosberg stem bark: an experimental-cum-computational investigation: Eur. Chem. Bull. 2023,12(10), 11411-11436. DOI: 10.48047/ecb/2023.12.10.806
- 8.Opoggen T. S.; Daniyan M. O.; Isaac D. Asiyanbola; Adeoye O. B.; Oyemitan I. A.: Effects of the essential oil of dried fruits of Piper guineense (Piperaceae) on neurological syndromes associated with cerebral malaria in mice: Universal Journal of Pharmaceutical Research 2023; 8(1): 61- 68. DOI: https://doi.org/10.22270/ujpr.v8il.902
- 9.Faloye K. O.; Adesida S. A.; Oguntimehin S. A.; Adewole A. H.; Omoyeni O. B.; Fajobi
- S. J.; Ugwo J. P.; Isaac D. Asiyanbola; Bamimore V. O.; Fakola E. G; Oladiran O. J.; Spiteller M.: LC-MS analysis, computational investigation, and antimalaria studies of Azadirachta indica fruit: Bioinformatics and Biology Insights. Volume 17: 1-9. DOI: 10.1177/11779322231154966
Research Interests
Assessment of selected natural products for potential drug lead in the management of cerebral malaria