UNIOSUN Staff Profile
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AJAYI Ebenezer Idowu Olatunbosun
Associate Professor
COLLEGE OF SCI. ENG. & TECH.
BIOCHEMISTRY
Brief Educational Profile
Postdoctoral Fellowship in Membrane Biophysics & Nanotechnology (CONICET Argentina, IMMF-UNC, Cordoba), 2018 to 2021
Ph.D. Membrane Biochemistry & Biotechnology (University of Ibadan), 2009 to 2015 (Ekiti State Indigenous Scholarship, 2008/2009)
Predoctoral Scholarship in Cardiovascular Diseases & Biosignalling (Nigeria TETFund, NIPER S. A. S. Nagar & CCMB Hyderabad India), 2012 to 2013
Predoctoral Fellowship in Pharmaceutical Biotechnology (TWAS-DBT, NIPER S. A. S. Nagar, India), 2010 to 2011
M.Sc. in Membrane Biochemistry & Biotechnology (University of Ibadan), 2006 to 2008
B.Sc. (Hons) Biochemistry (University of Ado Ekiti, now Ekiti State University), 1999 to 2004
Senior School Leaving Certificate (West Africa Examination Council, Christ's School Ado Ekiti), 1994 to 1999
Junior Secondary School Class One (Methodist High School, Ilesa), 1993 to 1994 (Transfer)
Primary School Leaving (Osun State Government Certificate), 1987 to 1993
Academic Profiles
ORCID
Google Scholar
https://scholar.google.com/citations?user=2TLdKU0AAAAJ&hl=en
ResearchGate
OpenAlex
Curriculum Vitae
Current/Recent Research
1. Evaluation of certain natural products for porcine pancreatic lipase and human pancreatic amylase inhibitory effects, in vitro.
2. Molecular screening of antimicrobial silver nanoparticles from indigenous African plants on wound-causing/-infecting Gram-negative microorganisms and tissue regeneration in skin fibroblasts.
3. Evaluation of certain natural products for the phenotypic control of obesity and diabetes in the fruitfly.
4. Targeting Plasmodium berghei apicoplast with African Polyherbal Formulations.
5. Protective potentials of flavonoid fractions of Nauclea latifolia and Bombacopsis bunopogensis in ulcerative colitis.
6. Trypanocidal and anti-leishmanial properties of extracts isolated from indigenous African plant parts.
Selected Recent Publications
- 1. Atanda J. A., Fadiya O. V., Muhibi M. A., Adeleke M. A., Ajayi E. I. O. (2020). Packed cell volume and Vitamin D levels in visceral leishmaniasis and diabetes mellitus co-morbidity among adults in Osun State, Southwestern Nigeria. Archive of Science & Technology 1:123 – 136. Publisher: Precious Cornerstone University.
- 2. Ajayi E.I.O., Molehin O.R., Iyoha E.I., Tallapragada S.P., Oloyede O.I., Tikoo K.B. (2021). Postmortem mitochondrial membrane permeability transition assessment of apoptotic cell death in brain and liver of diabetic, insulin-resistant, ovariectomised rats. IBRO Neurosci Rep. 11:156-163. Publisher: International Brain Research Organisation, Elsevier.
- 3. Olaniyan, O.P., Ajayi, E.I.O. (2021). Phytochemicals and in vitro anti-apoptotic properties of ethanol and hot water extracts of Cassava (Manihot esculenta Crantz) peel biogas slurry following anaerobic degradation. Clinical Phytoscience 7(77):1-11. Publisher: Springer Nature.
- 4. Adejumo, A.L., Azeez, L., Ajayi, E., Atere, T.G., Aderibigbe, F.A., and Adetoro, R.O. (2022). Characterization of acid soluble collagen from catfish (Clarias gariepinus) skin, its amino acid composition and its thermal stability. West Indian Journal of Engineering 44(2):14-19. Publisher: Faculty of Engineering, University of the West Indies, St. Augustine, Trinidad.
- 5. Adetunji J. B., Banji O. C, Ajayi E. I., Adekale A. I., Adeyomoye O. I. (2022). Anti-inflammatory efficacy of Corchorus olitorius seed and its effects on some biochemical and haematological parameters in egg albumin. Archive of Science & Technology 3(1): 95 – 107. Publisher: Precious Cornerstone University.
- 6. Cabral P. D., Silva G. B., Baigorria S. T., Juncos L. I., Ajayi E. I. O. and García N. H. (2022). Nitric oxide-inhibited chloride transport in cortical thick ascending limbs is reversed by 8-iso-prostaglandin-F2α. Kidney Res. Clin. Pract. 41(6):699-706. Publisher: The Korean Society of Nephrology.
- 7. Usman A., Balogun O., Shuaib B. I., Musa B. O. P., Yusuf A. A., and Ajayi E. I. O. (2023). Prevalence of cytopenia and its correlation with immunosuppression in naïve HIV-1 infected patients initiating first-line antiretroviral therapy: A pilot study. Infect Chemother. 55(4): 479-489. Publisher: The Korean Society of Infectious Diseases, Korean Society for Antimicrobial Therapy, and The Korean Society for AIDS.
- 8. Oladele O. T., Oladele J. O., Ajayi E. I. O., Alabi K. E., Oyeleke O. M., Atolagbe O. S., Olowookere B. D., and Bamigboye M. O. (2024). Bioactive composition and protective properties of Talium triangulare in dextran sodium sulphate-induced ulcerative colitis in rats. Pharmacological Research - Modern Chinese Medicine, 10:100344. Publisher: Chinese Pharmacological Society.
- 9. Oladele, J. O., Ojuederie, O. B., Oladele, O. T., Ajayi, E. I. O., Olaniyan, M. D., Atolagbe, O. S., Okoro O. E., Adewale O. O. and Oyeleke, O. M. (2024). Gastroprotective mechanism of Talinum triangulare on ethanol-induced gastric ulcer in Wistar rats via inflammatory, antioxidant, and H+/K+-ATPase inhibition-mediated pathways. Drug and Chemical Toxicology, 1–14. Publisher: Taylor & Francis.
- 10. Obasi J. N. and Ajayi E. I. O. (2025). Preliminary assessment of temperature, selected chemical modifiers and ions on frog heartbeat regulation. Res. J. Health Sci. 13(2): 215-222. Publisher: College of Health Sciences, Osun State University, Osogbo, Nigeria.
- 11. Oladele J. O., Ajayi E. I. O., Babatunde I. O., Awosanya O. O., Oladele T. O., Atolagbe O. S., Adewale O. O. and Oyedotun M. O. (2025). Neuroprotective efficacy of Talinum triangulare in cadmium-induced neurotoxicity: Involvement of antioxidant defense, anti-inflammatory, dopaminergic, and cholinergic systems. Metabolic Brain Disease, 40(6):237. Publisher: Springer.
- 12. Adekomi, D.A., Ogungbemi, D.I., Ibiyeye, R.Y., Adewale, O.O., Adekeye, O.O., Ajayi, E.I.O., Enye, L.A.., Edem, E.E., Onaolapo, A.Y., Adeniyi, T.D., Aderemi, A.V., Osuntokun, O.S., Ajadi, T.O., Adedayo, G.J., and Ajeleti, A.O. (2025). Pentazocine exposure elicits motor-social, neurochemical, and neuromorphological deviations in the cerebellum of juvenile male BALB/c mice. Nig. J. Neurosci. 16(3), 98-115. Publisher: Nigeria Society for Neuroscience.
- 13. Aderemi, A.V., Adesoye, O.J., Ayodabo, A.E., Idowu, O.G., Tokunbo, O.S., Olasunkanmi, A.T., Adeleke, I.A., Ajayi, E.I.O. (2025). Comparative effects of Monodora tenuifolia seed extract and Lirich® on alcohol-induced liver and kidney injury in rats. Res. J. Health Sci. Vol. 13(4): 448-460. Publisher: College of Health Sciences, Osun State University, Osogbo, Nigeria.
- 14. Fafioye R. O., Ajayi E. I. O., Ajilore B. S., Akinde S. B., Adeagbo O. Y. (2025). Association between Tcf7l2 Rs7903146 gene and cardiovascular disease development among diabetic patients attending Primary Health Centers in Osogbo, Nigeria. Pan African Journal of Life Sciences 9(3): 624 –630. Publisher: Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.
- 15. Ajayi E. I. O., Fadiya V. O., Adeyemi J. A., Muhibi M. A.,Adeleke M. A., Usman A. (2025). Screening and co-morbid association of visceral leishmaniasis and diabetes in Osun State, Nigeria. Nigerian Journal of Biochemistry and Molecular Biology. 40(1): 67-72. Publisher: Nigerian Society of Biochemistry and Molecular Biology.
- 16. Ozabor P. T., Oladele J. O., Ajayi E. I., Sholagbade G. A., Agoi O. O., and Fadahunsi I. F. (2026). Improvement of physicochemical properties and in vitro anti-inflammtory potentials of fermented cereals through synergistic fermentation and formulations. Food Bioscience 78:108498. Publisher: Elsevier
- 17. Adekomi D. A., Ajani H. A., Ibiyeye R. Y., Adekeye A. O., Enye L. A., Edem E. E., Adegoke A. A., Adewale O. O., Ajayi E. I. O., Adeniyi T. D., Osuntokun O. S., Idowu O. K., Hamed M. A., Dare B. J., Aderemi A. V.,Omotoso D. R., Atere T. G., Babatunde D. E., Ojo J. H., Ojo G. B., and Adekilekun A. T. (2026). Behavioural, neurochemical, and neurohistological effects of bisphenol A and vanadium following chronic co-administration in mice. IBRO Neuroscience Reports, 2026. Publisher: International Brain Research Organization.
Research Interests
Clinical/Membrane Biochemistry, Theranostic (Nano)Biotechnology, Mitochondria Genetics, Immunometabolic Complications (Diabetes, Obesity, Wound Healing, Cardiovascular Disorders, Cancer), Infectious Diseases-Related Neurobehavioural Disorders (Malaria, Leishmaniasis, Chagas, Dengue, HIV/AIDS; Alzheimer's, Parkinson's; Other Neglected Tropical Infectious Diseases & Neurodegenerative Disorders), Natural Product Therapeutics